Towards Highly Activating Leaving Groups: Studies on the Preparation of Some Halogenated Alkyl SulfonatesAuthor(s): Thomas Netscher | Patrick Bohrer
Journal: Molecules ISSN 1420-3049
Volume: 7; Issue: 8; Start page: 601; Date: 2002;
Keywords: Alkylation reagents | SN2 substitution reactions | steric hindrance | sulfonic esters | sulfur-oxygen bond cleavage.
The trichloromethylsulfonyl-, dichloromethylsulfonyl-, chlorosulfonyl-, and fluorosulfonyl esters of a neopentyl-type alcohol have been prepared via sulfonylation or sulfinylation followed by oxidation. The preparative usefulness and potential of the transformations are discussed.