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Synthesis of some pyridyl and cyclohexyl substituted 1,2,4 triazole, 1,3,4-thiadiazole and 1,3,4-oxadiazole derivatives

Author(s): Sattar Ebrahimi

Journal: European Journal of Chemistry ISSN 2153-2249
Volume: 1; Issue: 4; Start page: 322; Date: 2010;
Original page

Keywords: 1,2,4-Triazole | 1,3,4-Thiadiazole | 1,3,4-Oxadiazole | Thiosemicarbazide

ABSTRACT
New 1,2,4-triazoles (4a-c), 1,3,4-thiadiazoles (5a-c) and 1,3,4-oxadiazoles (6a-c) containing isomeric pyridyl and cyclohexyl were synthesized by intramolecular cyclization of 1,4-disubstituted thiosemicarbazides (3a-c) in alkaline media, acid and neutral condition respectively. The chemical structures of newly synthesized compounds were established with help of FT-IR, 1H-NMR and mass spectral data.