Synthesis of Pyran and Pyranone Natural ProductsAuthor(s): Christopher D. Donner | Melvyn Gill | Leonie M. Tewierik
Journal: Molecules ISSN 1420-3049
Volume: 9; Issue: 6; Start page: 498; Date: 2004;
Keywords: Stereospecific synthesis | fungal metabolites | quinones | isochromanones.
An overview of the synthesis of the fungal metabolites (+)-dermolactone, (Ã¢Â€Â“)- semixanthomegnin, (+)- and (Ã¢Â€Â“)-mellein, (Ã¢Â€Â“)-ochratoxin ÃŽÂ±, (Ã¢Â€Â“)-(1R,3S)-thysanone, the enantiopure ventiloquinones L, E and G, and 8-desmethyleleutherin from a common chiral intermediate, is presented. Further methodology leading potentially toward extended quinones such as (3S,3'S)-xylindein is also outlined.