Bilingual day care in Zurich Kinderkrippe Zürich
Kinderbetreuung in Zürich Kinderkrippe Zürich
Kita in Zürich Kinderkrippe Zürich
Kinderkrippe in Zürich Seebach Kinderkrippe Seebach
Academic Journals Database
disseminating
quality controlled scientific knowledge



Synthesis of Novel Azo Schiff Bases and Their Antibacterial and Antifungal Activities

Author(s): A. A. Jarrahpour | M. Motamedifar | K. Pakshir | N. Hadi | M. Zarei

Journal: Molecules ISSN 1420-3049
Volume: 9; Issue: 10; Start page: 815; Date: 2004;
Original page

Keywords: Schiff bases | azo compounds | antibacterial and antifungal activity | o-vanillin

ABSTRACT
Ten new azo Schiff bases 5a-h and 7a-b were prepared in excellent yields via the condensation of different aromatic amines and a new azoaldehyde, 2-hydroxy-3- methoxy-5-(4-methoxyphenylazo)benzaldehyde (4) by two different methods. All new compounds were tested against five microorganisms: Staphylococcus aureus (Gram positive and methicillin resistant), Bacillus subtilis (Gram positive), Kelebsiella pneumonia, Pseudomonas aeruginosa and Escherichia coli (all Gram negative). Compounds 4, 5a, 5c, 5d and 5g were moderately active against Staphylococcus aureus and Bacillus subtilis. Compound 7b was highly active against Bacillus subtilis and moderately active against Staphylococcus aureus. Other compounds were inactive against these strains of bacteria. The antifungal activities of these compounds were also tested against eight different fungal species. None of them were active against the fungi species tested.