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Synthesis of New Active Sulfones in the 5-Nitroimidazole Series

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Author(s): Kamel Benakli | Thierry Terme | Patrice Vanelle

Journal: Molecules
ISSN 1420-3049

Volume: 7;
Issue: 4;
Start page: 382;
Date: 2002;
Original page

Keywords: Nitroimidazoles | sulfones | electron transfer

ABSTRACT
We describe here the preparation of new 5-nitroimidazoles which are known to have an efficacy against metronidazole-susceptible and -resistant Giarda, Trichomonas, and Entamoeba spp. The multi-step synthesis uses electron transfer methodology.