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The Synthesis of Dicationic Extended Bis-Benzimidazoles

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Author(s): Zhijan Kang | Christine C. Dykstra | David W. Boykin

Journal: Molecules
ISSN 1420-3049

Volume: 9;
Issue: 3;
Start page: 158;
Date: 2004;
Original page

Keywords: DIBAL reduction | benzimidazoles | amidines | Bacillus subtilis.

ABSTRACT
The synthesis of extended dicationic bis-benzimidazoles starting from trans-1,2-bis(4-cyanophenyl)ethene and trans-1,2-bis(4-cyanophenyl)cyclopropane is reported. The target diamidines show significant in vitro activity against B. subtilis.
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