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The Synthesis of Dicationic Extended Bis-Benzimidazoles

Author(s): Zhijan Kang | Christine C. Dykstra | David W. Boykin

Journal: Molecules ISSN 1420-3049
Volume: 9; Issue: 3; Start page: 158; Date: 2004;
Original page

Keywords: DIBAL reduction | benzimidazoles | amidines | Bacillus subtilis.

ABSTRACT
The synthesis of extended dicationic bis-benzimidazoles starting from trans-1,2-bis(4-cyanophenyl)ethene and trans-1,2-bis(4-cyanophenyl)cyclopropane is reported. The target diamidines show significant in vitro activity against B. subtilis.