Academic Journals Database
Disseminating quality controlled scientific knowledge

Reactivity of 3-Ethoxycarbonyl Isoquinolinium Salts Towards Various Nucleophilic Reagents: Applications to the Synthesis of New 1,2-Dihydroisoquinoline-3-carboxylates

ADD TO MY LIST
 
Author(s): Mohamed Ameziane Aït Amer Meziane | Jean Pierre Bazureau

Journal: Molecules
ISSN 1420-3049

Volume: 7;
Issue: 2;
Start page: 252;
Date: 2002;
Original page

Keywords: 1 | 2-dihydro isoquinoline | lipophilic isoquinolinium | solvent-free quaternization | organolithium | alcoholate | N | O-acetal | domino reaction

ABSTRACT
Different types of novel 1,2-disubstituted 1,2-dihydro isoquinolines were synthesized by addition reactions of organolithium, alcoholates and borohydride reagents with various isoquinolinium salts. The leaving group character of the isoquinoline moiety was also evidenced.
     Coupon Page 40% off FileCure