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Production, Secretion and Biological Activity of Bacillus cereus Enterotoxins

Author(s): Sonia Senesi | Emilia Ghelardi

Journal: Toxins ISSN 2072-6651
Volume: 2; Issue: 7; Start page: 1690; Date: 2010;
Original page

Keywords: hemolysin BL | non-hemolytic enterotoxin | cytotoxin K | B. cereus

ABSTRACT
Bacillus cereus behaves as an opportunistic pathogen frequently causing gastrointestinal diseases, and it is increasingly recognized to be responsible for severe local or systemic infections. Pathogenicity of B. cereus mainly relies on the secretion of a wide array of toxins and enzymes and also on the ability to undergo swarming differentiation in response to surface-sensing. In this report, the pathogenicity exerted by B. cereus toxins is described with particular attention to the regulatory mechanisms of production and secretion of HBL, Nhe and CytK enterotoxins.