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New Synthetic Routes to Furocoumarins and Their Analogs: A Review

Author(s): Valery F. Traven

Journal: Molecules
ISSN 1420-3049

Volume: 9;
Issue: 3;
Start page: 50;
Date: 2004;
Original page

Keywords: Furocoumarins | furocoumarin analogs | psoralens | Fries rearrangements.

Many furocoumarins and their analogs possess a prominent photobiological activity. Some of them are successfully used as drugs in phototherapy of skin diseases. Fries rearrangement of acyloxyheteroarenes, condensation of acylhydroxyheteroarenes with α-carbonyl compounds under base catalysis and transformations of dihydrofurocoumarinones are new trends in synthesis of furocoumarins and their analogs.
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