A Method for Synthesizing Partially Substituted Cucurbit[n]urilAuthor(s): Anthony I. Day | Alan P. Arnold | Rodney J. Blanch
Journal: Molecules ISSN 1420-3049
Volume: 8; Issue: 1; Start page: 74; Date: 2003;
Keywords: Macrocycles | molecular binding | partially substituted
A novel approach to cucurbituril synthesis is described where partial substitution is introduced into cucurbit[n]uril. The identification of homologues (and their substitution) in reaction mixtures is achieved by a combination of ESMS and the use of the molecular probes (guests) 1,4-dioxane and 1,9-octanediamine. A unique symmetrical hexamethylcucurbit[3,3]uril, the major product, was isolated and characterized.