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Leishmanicidal Activity of Passifloricin A and Derivatives

Author(s): Wilson Cardona G. | Winston Quiñones Quiñones F. | Fernando Echeverri L.

Journal: Molecules ISSN 1420-3049
Volume: 9; Issue: 8; Start page: 666; Date: 2004;
Original page

Keywords: Passifloricins | antiparasites | δ-lactones | leishmanicidal activity

ABSTRACT
Several natural and hemisyntetic passifloricins were assayed against Leishmania panamensis amastigotes. High leishmanicidal activity as well as toxicity was observed. The structure of a new compound is also reported.