Academic Journals Database
Disseminating quality controlled scientific knowledge

Isolation and X-ray Crystal Structure of Tetrahydroisoquinoline Alkaloids from Calycotome Villosa Subsp. intermedias

Author(s): Ali El Antri | Ibtissam Messouri | Mohamed Bouktaib | Rachid El Alami | Michael Bolte | Brahim El Bali | Mohammed Lachkar

Journal: Molecules
ISSN 1420-3049

Volume: 9;
Issue: 8;
Start page: 650;
Date: 2004;
Original page

Keywords: Calycotome villosa (Poiret) Link Subsp. Intermedia | alkaloids | tetrahydroisoquinoline | spectroscopy | X-ray crystal structure determination.

Two tetrahydroisoquinoline alkaloids were extracted from the alkaloid fraction of a methanol extract of the seeds of Calycotome Villosa Subsp. intermedia. Their structures were established as (R)-1-hydroxymethyl-7-8-dimethoxy-1,2,3,4-tetrahydro- isoquinoline (1) and (S)-7-hydroxymethyl-2-3-dimethoxy-7,8,9,10-tetrahydroisoquinoline chloride (2) by spectroscopic techniques and X-ray diffraction analysis.
     40% off discount for PC Health Advisor