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Clinical, Dermatoscopic, and Histopathological Features of Spitz Nevus - Original Article

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Author(s): Sibel Ersoy Evans | Özge Gündüz | Gül Erkin | Gonca Boztepe | Sedef Şahin | Özay Özkaya

Journal: Turk Dermatoloji Dergisi
ISSN 1307-7635

Volume: 02;
Issue: 04;
Start page: 93;
Date: 2008;
Original page

Keywords: Nevus | epithelioid and spindle cell nevus | dermoscopy

ABSTRACT
Aim: Spitz nevus is a benign, mostly acquired melanocytic nevus, which is commonly seen in childhood. The aim of this study was to describe the clinical, dermatoscopic, and histopathological features of Spitz nevus.Methods: Clinical data, histopathological slides, and dermatoscopic images of the patients that were histopathologically or clinically diagnosed with Spitz nevus between 2000-2005 were retrospectively analyzed. For statistical analysis, descriptive statistics and chi-square tests were used.Results: Among the 30 patients included in the study, 56.7% were female. Median patient age was 15.5 years (range: 3-49 years) and 40% were younger than 12 years of age. The most frequent clinical diagnoses before biopsy were Spitz nevus (33%) and melanocytic nevus (30%). Median disease duration was 12 months (range: 1month-20 years) and mean diameter of the lesions was 5 mm. Lesions were most commonly localized on the lower extremities (44.8%) in both children and adults, and lower extremity localization was more common in females (P=0.007). The most common histopathological types noted were Spitz nevus 53.5% (n=15) and Reed nevus 32% (n=9). Dermatoscopy was performed in 16 patients; 31.3% had reticular pattern, 18.8% had starburst pattern, and 18.8% had atypical pattern.Conclusion: Spitz nevi were seen in both children and adults. Pigmented Spitz nevus, which resembles melanocytic nevus, was the most common type and lower extremity localization was more common in females.