Histoplasmin reaction. Comparison of a polysaccharide antigen to the filtrate antigen

Author(s): FAVA Særgio Di Camilo, RIVITTI Evandro A., CUCí‰ Luiz Carlos, WEISS Simone, RIGONE Gianine, FAVA-NETTO Celeste
Keywords: Reaction to histoplasmin, Filtrate antigen, Polysaccharide antigen
Journal: Revista do Instituto de Medicina Tropical de São Paulo
Year: 1997
Full text: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651997000500003
Publisher: Instituto de Medicina Tropical
Abstract: This work was planned by taking into account all the knowledge accumulated from the immunological study of paracoccidioidomycosis. It aimed at comparing a polysaccharide antigen from Histoplasma capsulatum to a classic histoplasmin with the help of intradermal tests of delayed type of hypersensitivity. Tests were applied to 115 individuals in Santo Amaro, a town in the state of São Paulo. Positive results using classic histoplasmin were obtained in 46.0% cases whereas positive results using the polysaccharide antigen at its hightest concentration were obtained in 51.30% cases. The major conclusion in this investigation is that it is possible to use the polysaccharide antigen as histoplasmin instead of the filtrate antigen