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2-Arylhydrazonopropanals as Building Blocks in Heterocyclic Chemistry: Microwave Assisted Condensation of 2-Arylhydrazonopropanals with Amines and Active Methylene Reagents

Author(s): Khadijah M. Al-Zaydi | Rita M. Borik | Mohamed H. Elnagdi

Journal: Molecules
ISSN 1420-3049

Volume: 8;
Issue: 12;
Start page: 910;
Date: 2003;
Original page

Keywords: 2-Arylhydrazonopropanals | heterocyclic amines | active methylene compounds | microwave irradiation | X-ray structures

Utilization of 2-arylhydrazonopropanals for the synthesis of 2-arylhydrazonoimino propanones, 1,2,4-trizolo[4,3-a]pyrimidines, pyridopyridazine hydrazones, 3-oxaloalkanonitriles and 1,2,3-trizole derivatives by conventional heating and under microwave irradiation is described. Structural assignments are based on spectroscopic data and confirmed in some cases by X-ray crystallography.
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